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Variation in the cycle is usually due to differences in the proliferative phase as collapse of the secretory phase into menstruation if fertilisation does not take place is relatively more predictable than the proliferative phase.
In the endometrium, proliferative activity occurs even before the complete cessation of menstruation, i.e. The glands at this earlier stage are relatively straight or, at most, slightly coiled and are found within relatively loose endometrial stroma.
Method To ensure a good specimen for morphologic interpretation, a biopsy sample should be taken from both the anterior and the posterior endometrium and fixed immediately in 10% buffered formalin.
In current practice, the device that is most often used is the Pipelle endometrial aspirator.
Steroid hormone control of endometrial, epithelial, stromal, and presumably endothelial cells is mediated by estrogen receptors and progesterone receptors. They have high affinity to bind estradiol and progesterone, respectively.
If I am unable to answer your question and a personal visit is necessary, please see me at the following clinics: Asian Hospital & Medical Center Room 512 Medical Office Building Mon – Sat – pm Call 659-0058 or 096 (ASIAN) for appointments Suite 1706 Medical Plaza Makati Building (Behind Makati Medical Center) Friday 1-2pm ( strictly by appointment only) For Questions, you may text 2685-27426 (ASIAN) Click here to view the maps to the clinics.In cases in which little or no tissue is obtained but the endometrium was penetrated with the aspirator, a repeat procedure should be performed.If the repeat aspiration still yields little tissue, one can assume severe endometrial atrophy or obstructing endometrial polyp.The interval phase occurs over a short period of 24-48 hours.1-2 days following ovulation, there is a peak of luteinising hormone and increased progesterone, which brings on the secretory changes.